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McKay Law’s Xeljanz Lawsuit Lawyers

McKay Law is eager to boldly fight and protect anyone who may be the victim of health problems resulting from taking Xeljanz!

What should you do when a medication makes you feel worse, not better? Whether it’s over-the-counter medicine or a prescription from a doctor, drugs are meant to treat a patient. When side effects exceed the benefits, medicines can become very dangerous and sometimes lethal.

Pharmaceutical companies and suppliers have an ethical and legal responsibility to properly disclose the risks and side effects of a drug before bringing it to market. Unfortunately, these warnings are often withheld in the name of profit.

Pfizer’s Xeljanz (tofacitinib) has been on the market since 2012. First approved to treat rheumatoid arthritis, Xeljanz has since received FDA approval for the treatment of other types of arthritis as well as ulcerative colitis.

In just the last two years, however, the FDA has warned that Xeljanz can be associated with heart problems, blood clots, and even cancer. But the question remains: why didn’t Pfizer warn consumers about these potential risks sooner?

Xeljanz lawsuits claim that Pfizer failed to give adequate warning about the drug’s side effects, which caused preventable harm to patients who suffered blood clots in the lungs, heart attacks, strokes, breast and colon cancer, and other severe health problems. McKay Law’s dangerous drug lawyers are accepting these cases on a contingency fee basis. That means our clients don’t pay unless we win. If you need to discuss a lawsuit with our Xeljanz lawyers, free of charge, please contact us.

About Xeljanz

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Xeljanz belongs to a class of drugs known as Janus kinase (JAK) inhibitors. As Pfizer explains, our body has signaling proteins called cytokines that regulate immune system responses. The production of cytokines is increased when our body fights infection. Cytokine production is thought to play a role in chronic inflammatory conditions, such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Xeljanz disrupts signaling that produces some of the cytokines, reducing inflammation. Specifically, Xeljanz blocks—or inhibits—the release of cytokines in the JAK signal pathway.

Xeljanz has been approved for several different uses:

  • 2012: FDA approves Xeljanz for rheumatoid arthritis
  • 2017: FDA approves Xeljanz and Xeljanz XR (extended release) for psoriatic arthritis
  • 2018: FDA approves Xeljanz for ulcerative colitis
  • 2020: FDA approves Xeljanz for polyarticular juvenile idiopathic arthritis

According to the Xeljanz website, about 132,000 Americans were prescribed the drug between January 2013 and July 2018 to treat rheumatoid arthritis. Many more patients may have been prescribed the medication it to treat ulcerative colitis or psoriatic arthritis. Pfizer reported it made about $1.7 billion off the drug in 2018.

Post-Marketing Xeljanz Study Reveals Serious Safety Concerns

Most Americans assume that if a drug is approved by the FDA, it has been thoroughly evaluated for safety and efficacy. However, this isn’t always the case. In addition to pre-approval clinical testing, the FDA may order post-marketing studies as a condition of drug approval. These trials gather more information about a drug’s safety, efficacy, or optimal use.

When the FDA first approved Xeljanz in 2012, it ordered a post-marketing safety study known as ORAL Surveillance. But rather than confirming the safety of Xeljanz, results of this study has caused concern leading to new health alerts and warnings.

Xeljanz and Blood Clots

In February 2019, the FDA warned that the ongoing Xeljanz safety trial found an increased risk of blood clots in the lungs and death. In July 2019, the FDA announced that it had approved new warnings about thrombosis and death in patients treated with a 10 mg twice-daily dose of Xeljanz.

Thrombosis occurs when a blood clot blocks a vein or artery. Deep vein thrombosis, pulmonary embolism, and arterial thrombosis have all been reported in Xeljanz patients.

  • A blood clot in a deep vein is known as a deep vein thrombosis (DVT). DVT usually occurs in the legs.
  • A blood clot that travels to the lungs is called a pulmonary embolism (PE). PE is usually caused by a blood clot that starts in the arm or the leg.
  • Arterial thrombosis is a blood clot in an artery. This type of thrombosis can stop blood from reaching vital organs.

Blood clots can lead to a heart attack, stroke, organ damage, and even death. Symptoms of a blood clot include:

  • Sudden shortness of breath
  • Chest pain that gets worse with breathing
  • Swelling of the arms or legs
  • Leg pain or tenderness
  • Red or discolored skin in the painful or swollen leg or arm
Pfizer | Xeljanz Side Effects | McKay Law

Xeljanz and Cancer

The next major safety news to come out of the Xeljanz post-marketing study was equally concerning. The FDA alerted the public in February 2021 that preliminary results showed an increased risk of cancer with Xeljanz.

Pfizer reports in a press release that malignancies observed in Xeljanz studies include (but are not limited to):

  • Lymphoma
  • Melanoma
  • Lung cancer
  • Breast cancer
  • Prostate cancer
  • Pancreatic cancer

Xeljanz and Cardiovascular Problems

Also in February 2021, the FDA warned about serious heart-related problems that may result from Xeljanz use. Pfizer refers to these in its press release as “major adverse cardiovascular events” (MACE).

Pfizer reports that a total of 135 patients in the study had a major adverse cardiovascular event, although the full results have not yet been released. The most frequently reported event was myocardial infarction (i.e. heart attack).

  • Other cardiac events that may be linked to Xeljanz include:
  • Cardiac arrest
  • Cardiovascular death
  • Ischemic stroke
  • Acute coronary syndrome
  • Heart failure
  • Atrial fibrillation


How Dangerous Is Xeljanz?

Xeljanz, while marketed as a safe medication, increases the risk of blood clots, cancer, and cardiovascular problems for its users. The FDA approved the drug upon release, but a post-marketing safety study concluded that the side effects are more detrimental than initially believed. The company responsible for the medication, Pfizer, knew about the side effects prior to the safety study but failed to disclose this information to the public in an attempt to retain their profits. This unethical behavior exposed thousands of consumers to an elevated risk of harm, making their actions unacceptable by any means.

Why Is Xeljanz a Dangerous Drug?

Xeljanz first entered the market in 2012, and we’re only now beginning to understand the severity of its side effects. Medication is different from a traditional product because all outcomes are biological, meaning that the effects are internalized and more challenging to recover from in the case of injury. The caliber of Xeljanz’s side effects make it significantly dangerous to the consumer, and the company’s failure to disclose the risk only makes it worse because many people were unaware of their elevated risk. 

How Long Can You Stay on Xeljanz?

Anyone who is currently using Xeljanz should speak with their doctor about terminating their prescription to avoid the dangerous side effects. Not only will they help you stop the drug, but they can also advise you on safe medication alternatives for your condition.

Can Xeljanz Cause Cancer?

Unfortunately, some users of Xeljanz have developed cancer as a result of their medication use, including but not limited to lymphoma, melanoma, and lung cancer. Pfizer, already knowing the risk of the drug’s side effects, sold it to consumers anyway, causing many innocent individuals to develop and suffer from a life-threatening disease. Their reluctance to disclose the risk of their product isn’t just unethical, it’s illegal, and our attorneys are here to help hold them accountable to the full extent of the law.

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McKay Law Protects the Rights of Injured People

Taking on a big pharmaceutical company requires a big law firm to support you. McKay Law has the resources, strength, and skill to successfully challenge big drug companies like Pfizer in court. And we handle every case on a contingency-fee basis, so our clients don’t pay a dime unless we recover money for them.

We are currently speaking to clients across the country about Xeljanz cancer, blood clot, and cardiovascular lawsuits. Patients who took Xeljanz as prescribed and developed a malignancy, thrombosis, or heart-related issues may qualify for a lawsuit. Lawsuits against Pfizer can recover compensation for medical bills, lost wages, pain and suffering, reduced quality of life, and more.

Free consultation 24/7 with McKay Law’s Xeljanz lawsuit lawyers. 
Call us today or submit your case.

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Latest Articles from Our Texas Xeljanz Lawsuit Lawyer

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In 2019, The FDA has linked Xeljanz to the following serious side effects: cancer, cardiovascular events, and venous thromboembolism. Xeljanz Side Effects: Major Adverse Cardiovascular Events Xeljanz has been linked to a greater rate of major adverse cardiovascular events, including: Cardiac arrest Cardiovascular death Congestive heart failure Coronary revascularization Myocardial

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